Overview
CCFD Pharma Vision
Continuous automatic filtration, washing and drying with innovative vision system for fine control over filtration and washing
State-of-the-art vision system automatically stops filtration and washing before dryland!
From feasibility through optimization to production on a single validateable platform!
The DN20 CCFD Pharma Vision achieves accurately controlled automatic filtering, washing, deliquoring as well as nitrogen/air drying, discharge of dry solids and Wash in Place. It consists of ten 20 mm diameter, 50 ml capacity filtration chambers.
Vision System
Automatic dryland detection!
Accurate auto-dispense of wash volume based on measured cake volume!
Improves product purity, yield and quality attributes!
Improves wash efficiency!
Reduces solvent usage!
Reduces energy and waste!
CCFD Pharma Vision - Functionality
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Vision system for automated fine control of filtration and washing processes
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Auto transfer from external process into jacketed slurry buffer vessel
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2 x Wash dispense systems (vessel, pump, valves)
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WIP dispense system (vessel, pump, valves)
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Heated Nitrogen/Air drying system with temperature control
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Filtrate receiver with Auto-drain feature
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Filtrate/wash sampling bottles for offline analysis
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Adjustable filtration/washing/drying parameters
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Auto-data population, recall and presentation
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Auto Wash in Place during auto-operation
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End of day automated cleaning routine
Operational Advantages
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Optimisation Mode: Process one aliquot automatically
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Production Mode: Auto-operation for maximum throughput
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Non-settling Mode: For processing non-settling slurries
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Manual Mode: Operation of all processes
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Auto-calibration feature
CCFD Pharma Vision - Options
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Nitrogen Blanketing System
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Cooling vessel for Wash Solvent
HMI Control Panel
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Local HMI or DCS control
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Compile, store and retrieve 100 recipes
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Auto data population recall and presentation
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Full data-logging to allow Darcy plots to be generated and filtation conditions optimised
CCFD Pharma Vision - Process Sequence
Port 1
1st Wash - Stops draining before dryland
Port 2
3rd Wash - Drain and Deliquor
Port 3
Port 4
Port 5 - 9
2nd Wash - Stops draining before dryland
Drying - Heated Nitrogen/Air
Filtration - Stops before dryland
Port 10
Cake Discharge
AWL CCFD VISION - KEY ADVANTAGES
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Ability to stop at or just before dryland!
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Accurate control of filtration and washing within 1 ml!
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Automated dispense of wash volume based on measured cake height!
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Significantly reduced solvent usage
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Improved product purity, yield and quality attributes
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From feasibility through optimisation to production on a single validateable platform
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Optimisation of filtration and washing parameters can be achieved within a few hours and only requires a small sample volume… Minimum Throughput, Maximum Data!